LTC4S and acute myeloid leukemia: Nevertheless, an upregulation was observed in fumarylacetoacetate (p≤0.014), and LTC4 synthase (p≤0.014), HOXA9 (p≤0.01), and c-myb (p≤0.01) in the CD34 positive and negative fractions, in AML, in comparison with normal BM (Fig 4).