LEP and Beta-thalassemia: These findings are in line with the results of our study that proved the serum leptin level had highest amount for the ages older than 10 years (24).Musallam KM did a 10 years follow-up study on serum ferritin level in transfusion-independent patients with beta-thalassemia and concluded that the ferritin level increased after ten years for the same patients which is in line with our findings (25).