BRCA1 and neoplasm: Finally, in Cal-27 cells with stable BRCA1 expression, we observed that the inhibition of tumor growth (Figure 6G and 6H, Supplementary Figure S8G) was attenuated by BRCA1 in response to cisplatin treatment while BRCA1 expression and miR-593-5p levels were increased(Supplementary Figure S8H and 8I).