CXCL8 and thyroid cancer: 1992; Strieter et al. 1995). In a model of thyroid cancer, Bauerle and colleagues (Bauerle et al. 2014) showed that NF-κB regulated the expression of IL-8, which enhanced tumor cell growth in vivo and endothelial cell tube formation in vitro. IP-10 is another member of the CXC family of cytokines, but contrary to IL-8, it is angiostatic and signals through the CXCR3 receptor (Romagnani et al. 2001; Mehrad et al. 2007).