SHC1 and infection: There is also a significant effect of time [F (1, 29) = 0.942, P = 0.342], titer [F (2, 29) = 8.426, P = 0.0019] and a time×titer [F (2, 29) = 9.976, P = 0.00082] interaction on the defecation response after pAd-miOlr81 infection, which at the high final titer in Elvax (7.00 ×107 GFU/ml) alleviated the defecation response to rotation in MSS animals when compared to their pre-Elvax treatment data (P = 0.0062); No significant effects were observed after pAd-Shc1 treatment.