Interestingly, we found that the expression HRAS alleles sensitized two out of three cancer cell lines (H3122 and HCC827) to starvation, while HCT116 cells were not sensitized, possibly because this cell line already harbors a mutated KRAS, which may make these cells less affected by the genetic manipulation that we performed (Figure 3E-G). This evidence concerns the gene KRAS and cancer.