SCGB1A1 and neoplasm: To evaluate the anti-tumor effect of the BA derivatives in vivo, we used xenograft models and transgenic mice that develop spontaneous lung tumors following doxycycline treatment in Scgb1a1-rtTA/TetO-Kras4bG12D and Scgb1a1-rtTA /TetO-EGFRL858R mice.