We observed that the CCGT (APOA5*2) haplotype determined by the combination of alleles -1131C, c.56C, c.553G and c.1259 T is associated with the MS (OR = 3.223, 95% CI:1.43- 7.25, p = 0.00278), but no association was found with biochemical parameters. Here, APOA5 is linked to myeloid sarcoma.