Among the Hungarian population, the APOA5*2 haplotype (the combination of -1131 T > C, IVS3 + 476G > A and 1259 T > C SNPs) confers risk for the development of MS (OR = 2.880; 95% CI: 1.567-5.292; p = 0.001), and a novel haplotype APOA5*5 (1259C allele alone) with a protective effect against MS was identified [26]. This evidence concerns the gene APOA5 and myeloid sarcoma.