Regarding NKG2D (Figure 1, panel E), AIDS-RL patients with <300 CD4+ lymphocytes/mm3 had a lower expression of NKG2D than AIDS-RL patients with >300 CD4+ lymphocytes/mm3 (M = 15.92 IQR[8.125-29.93] vs 29.18[18.18-41.32], p = 0.036), than HIV + patients without lymphoma but >300 CD4+ lymphocytes/mm3 (M = 24.92 IQR[18.68-35.45], p = 0.005), than HIV-negative lymphoma patients (M = 31.89 IQR[25.71-42.17], p = 0.001), or than HS (M = 31.78 IQR[27.40-37.50], p = 0.001). This evidence concerns the gene KLRK1 and AIDS.