On analyses of the baseline demographic and clinicopathological characteristics, sex and the primary tumor sites were found to significantly differ between the two groups, whereas other variables such as the age, BMI, ECOG-PS, ASA score, CEA, KRAS status, depth of invasion, lymph node metastasis, sum of the longest tumor diameter, number of metastases, number of organs with metastasis, peritoneal dissemination, and chemotherapy regimens did not significantly differ (Table 1). This evidence concerns the gene CEACAM5 and metastatic malignant neoplasm in the lymph nodes.