While up-regulated DEGs at 72 h post-transduction were significantly enriched in amino acid metabolism pathway, and down-regulated DEGs were enriched in focal adhesion, regulation of actin cytoskeleton and pathway in cancer, specifically ATCB (actin, beta), ITGA2 (integrin, alpha 2) and PDGFRA (platelet-derived growth factor receptor, alpha polypeptide). The gene discussed is ACTB; the disease is cancer.