We also sequenced tumor DNA of 90 APAs, including 40 that did not have mutations in previously implicated genes (KCNJ5, CACNA1D, ATP1A1, ATP2B3, and CTNNB1 [Choi et al., 2011; Azizan et al., 2013; Beuschlein et al., 2013; Scholl et al., 2013]). Here, CACNA1D is linked to neoplasm.