We next also determined the surface and total levels of EphA2 during the mid-phase infection with Ctr-serovar D. Like for serovar L2, surface EphA2 expression of cells infected with Ctr-serovar D was similar at three different time points of infection (14, 20 and 28 h p.i.)whereas permeabilised-infected cells displayed an increase of intracellular EphA2 levels (Fig 10E). The gene discussed is EPHA2; the disease is infection.