NEUROD2 and neoplasm: Grade 3 (p = 0.026), high mitotic count (>8 mitoses/2 mm2; p = 0.028), large tumor size (>2.0 cm; p = 0.031), luminal type B (p = 0.042), positive HER2 status by CISH (low and high level amplification; p = 0.039), NEUROD2 copy number gain (p = 0.015), HER2 copy number gain (p = 0.015) and whole chromosome 17q arm gain (p = 0.010) were found to be associated with a decreased 5 year survival rate.