Currently, much research is focused on this hotspot, and it has been confirmed that many biological factors are associated with NSCLC development and prognosis, such as matrix metalloproteinase (MMP)-2[7], MMP-9 [8], transforming growth factor (TGF) [9], and cyclophilin A (CypA) [10]. Here, PPIA is linked to non-small cell lung carcinoma.