Furthermore, diabetes up-regulated the genes of phase I and II detoxification enzymes such as, CYP2J4, CYP1A1, P450 (cytochrome) oxidoreductase, Nat8, GCNT2, GSTYc2. Such significant increases in these genes indicate the rise of diabetic detoxification processes which is also confirmed by pathway analysis. Here, GCNT2 is linked to diabetes mellitus.