TNF and rheumatoid arthritis: Day 14 shows no more difference between osteogenic medium alone and cytokines in OA FLS (Figure 2A), while in RA FLS, TNF-α alone or in combination to IL-17A showed a significant increase (6-fold with TNF-α and 7.3-fold with TNF-α + IL-17A vs. 2.2-fold without cytokine, **p < 0.005).