TRH and infection: The majority of infections in the Northeast were caused by trh-containing, urease positive strains (Tables 2, 3, Supplementary Table 1), and both attributes are used for assignment of environmental isolates as pathogens since trh-containing strains have increased among clinical isolates in North America in recent years (Tables 2, 3) (Jones et al., 2012; Martinez-Urtaza et al., 2013; Banerjee et al., 2014).