We have shown that T cells from both naïve splenocytes and tumor antigen-sensitized draining lymph nodes (DLN) could be expanded with exposure to interleukins (IL)-7 and 15 after activation with bryostatin and ionomycin (B/I) to significantly greater numbers than the current standard approach using IL-2 alone [6]. The gene discussed is IL2; the disease is neoplasm.