Most previous mutation analyses of T-ALL have focused on only one or a few candidate genes, for example ETV6 (12p13.2), FBXW7 (4q31.3), FLT3 (13q12.2), IL7R (5p13.2), IRS4 (Xq22.3), JAK1 (1p31.3), NOTCH1 (9q34.3), NRAS (1p13.2), and TP53 (17p13.1). Here, FLT3 is linked to acute lymphoblastic leukemia.