In humans, mutations in several centrosomal proteins, such as PCTN, STIL, CEP152, CEP135, CEP63 and CENPJ, have been associated with autosomal primary recessive microcephaly (MCPH), Majewski Osteodysplastic Primordial Dwarfism type II and Seckel syndrome15, 16, 17, 18, 19, 20, 21. This evidence concerns the gene CEP63 and autosomal recessive primary microcephaly.