As with the original DMG-alone analysis, the MEGs were also significantly 3.75-fold enriched in the KEGG ‘Rheumatoid arthritis‘ pathway (q = 1.70E-02, where q is a multiple-test corrected P-value) with 7 out of 89 genes: ANGPT1, CSF2, CTLA4, HLA-DQA1, HLA-DQA2, HLA-DRA and HLA-DRB1. This evidence concerns the gene CTLA4 and rheumatoid arthritis.