IFNG and infection: Ifnγ had significant increases in transcript levels at the site of infection on Days 4 and 7 (LFC = 4.15 and 4.43, respectively; S1 Table), and its pathway was also predicted through URA as activated locally at Days 1, 4, and 7 after challenge because a large number of genes affected by IFNγ demonstrated expression patterns indicative of pathway activation (S2, S4 and S6 Tables).