By attracting and activating immune cells, CCL2 plays a pivotal role in many inflammatory processes and has been shown to be involved in a wide variety of diseases with or without an obvious inflammatory aspect as, for example, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, atherosclerosis, allergy and asthma, diabetic retinopathy, lupus nephritis, diabetic nephropathy and others5, 6, 7. The gene discussed is CCL2; the disease is diabetic kidney disease.