SMARCB1 and neoplasm: Mutations in genes of the chromatin remodeling pathway have been described in various types of neoplasms such as malignant rhabdoid tumors [85], atypical teratoid/rhabdoid tumors of the brain [86,87,88] and hypercalcemic type of ovarian small cell carcinomas [6,7,8]; these mutations target closely related genes SMARCA and SMARCB that regulate this pathway, which is not particular of these neoplasms: SMARCB1 homozygous deletions have been found in epithelioid sarcoma and a subset of myoepithelial carcinomas [87].