To further substantiate that ethyl acetate fraction of SA, PT, and HT polyphenols regulate crucial and defined autophagic players that functionally orchestrate PC survival after first-line therapy, we examined the cellular expression levels of ATG3, ATG5, ATG12, survivin, LC3A, LC3B, and beclin in residual human PC tumors. Here, ATG12 is linked to pachyonychia congenita.