To further substantiate that ethyl acetate fraction of SA, PT, and HT polyphenols regulate crucial and defined autophagic players that functionally orchestrate PC survival after first-line therapy, we examined the cellular expression levels of ATG3, ATG5, ATG12, survivin, LC3A, LC3B, and beclin in residual human PC tumors. This evidence concerns the gene ATG5 and pachyonychia congenita.