Paroxysmal Nocturnal Hemoglobinuria (PNH) is an acquired clonal disorder of hematopoietic stem cells due to somatic mutations in the PIG-A gene, with an early block in the synthesis of the glycosylphosphatidylinositol (GPI) anchor on the cell membrane [1]. This evidence concerns the gene PIGA and paroxysmal nocturnal hemoglobinuria.