Given the potent inhibitory effect on cell proliferation of NASTRp, we extended lung cancer cells to lung cancer cell lines harboring EGFR mutations, NCI-H1975 (EGFR-L858R/T790M) and a squamous cell carcinoma with highly expressing FGFR and CREB, NCI-H520 (IC50 = NCI-H1975, 8.891 μM; NCI-H520, 4.363 μM; ref. [11]). The gene discussed is CREB1; the disease is squamous cell carcinoma.