MGMT and malignant glioma: Genomic biomarkers of malignant glioma include isocitrate dehydrogenase 1/2 (IDH1/2) mutations, O-6-methylguanine-DNA methyltransferase (MGMT) promoter methylation status and 1p19q co-deletion, and these markers provide information on prognosis and response to treatment [4-6].