FZHY tablet exhibits antifibrotic activity by inducing apoptosis in HSC-T6 cells through p38 and SAPK/JNK pathways [99,104], and inhibits liver fibrosis through decreasing transcription of TIMP-1, PDGF-B, and PDGF receptor β1 in vivo [99]. This evidence concerns the gene MAPK14 and Hepatic fibrosis.