NFKB1 and acute lymphoblastic leukemia: Nobiletin (3′,4′,5,6,7,8-hexamethoxyflavone, Figure 2), the active component of Citrus unshiu peel, markedly inhibited HCV absorption in the human lymphoblastic leukemia MOLT-4 cell line [57] and reduced hepatic inflammation through reducing iNOS and DNA-binding activity of nucleus NF-κB [58].