KLF5 and Familial prostate cancer: In the latest genome-wide copy number change studies, KLF5’s deep deletion, which likely indicates homozygous deletion, has been detected in 10% of prostate cancers in The Cancer Genome Atlas (TCGA) database (tcga-data.nci.nih.gov) and in 20% of metastatic prostate cancers in another database [53], as analyzed by the cBioPortal program [54,55].