ZEB1 and neoplasm: Previous studies have found that molecules such as miR200c, ZEB1 and transforming growth factor β (TGF-β), can potentially regulate tumor progression [4, 10, 11], and that the overexpression of miR200c or the knockdown of TGF-β1 or ZEB1 could inhibit the tumor cell EMT program that activates cellular mobility and subsequent tumor metastasis [12-14], in particular, the TGF-β1 signaling blockade has proven to be efficient in preventing the development of a variety of tumor types [15].