As shown in Figure 3A-B and S2 (for LNCaP and C4-2 cells), recruited HMC-1 cells or conditioned media (CM) after co-culture with PCa cells could decrease AR expression at both protein and mRNA levels in all four PCa cell lines (LNCaP, C4-2, C4-2B and CWR22RV1). This evidence concerns the gene AR and posterior cortical atrophy.