However, ART-mediated viral suppression did not restore the frequency of CD161++ MAIT cells in HIV mono-infected treated patients (median, 1.38%; range, 0.16–3.4, P = 0.7) relative to HIV mono-infected treatment naïve patients (median, 0.82%; range, 0.15–6.8) and HIV/TB co-infected treated patients (median, 1.44%; range, 0.05–8.7; P = 0.5) in comparison with HIV/TB co-infected treatment naïve patients (median, 0.75%, range, 0.085–2.3) (Fig 2B). This evidence concerns the gene KLRB1 and tuberculosis.