SDHC and hepatocellular carcinoma: As shown in Table 2, SNPs rs12064957 and rs3935401 in SDHC gene were significantly associated with increased HCC overall recurrence risk under recessive (HR = 2.01, 95%CI 1.02–3.96, P = 0.044) and additive (HR = 1.24, 95%CI 1.00–1.53, P = 0.049) models, respectively.