Positive VEGFR-1 staining was seen in 869 of our 2669 (32.6%) interpretable prostate cancers and was considered weak in 24.2%, moderate in 6.7% and strong in 1.7% of cancers, while 1800 (67.4%) did not show any membranous VEGFR-1 reactivity. This evidence concerns the gene FLT1 and cancer.