The frequency of detectable VEGFR-1 staining is substantially lower in our study than in four earlier publications reporting VEGFR-1 expression in 97.5%, 100% and 100% analyzing 40, 15 and 113 prostate cancers and in 100% of 16 pelvic lymph node metastasis [21,22,23,25]. Here, FLT1 is linked to Familial prostate cancer.