Multivariate analysis revealed that strong VEGFR-1 expression remained a significant predictor of disease outcome (p = 0.02), if pathological tumor stage (p < 0.0001), Gleason grade (p < 0.0001), nodal stage (p < 0.0001), resection margin (p < 0.0001) and pre-operative PSA (p = 0.05) were included into the analysis (Table 2). Here, KLK3 is linked to neoplasm.