This is demonstrated by the fact that the AD-CST3 association, validated by candidate gene meta-analysis (Hua et al. 2012), has also not been reported in any GWAS for AD (Harold et al. 2009; Hollingworth et al. 2011; Lambert et al. 2009; Naj et al. 2011; Seshadri et al. 2010), nor a GWAS meta-analysis (Lambert et al. 2013). The gene discussed is CST3; the disease is Alzheimer disease.