Following CD3 stimulation, MuSK-MG patients showed higher Th1 related IFN-γ, Th17 derived IL-17A and T follicular helper (Tfh) associated IL-21 production than CON (p = 0.016, p = 0.04 and p = 0.01, Fig 1A–1C). Here, MUSK is linked to myasthenia gravis.