Proinflammatory chemokines demonstrated their importance in HCC-specific T-cell immunity, such as IFN-g-inducible chemokines CXCL9/Mig and CXCL10/IP-10, high levels of which correlated with the presence of CD8+ T cell in hepatocarcinoma. This evidence concerns the gene CXCL10 and hepatocellular carcinoma.