Inflammatory cytokines, like type I and type II interferons and IL-6, IL-1, and TNF-α as well as immunomodulatory cytokines like IL-10 and transforming growth factor β (TGF-β), have been identified as important players in SLE and are present in the tear of dry eye patients [30]. Here, SGCG is linked to Keratoconjunctivitis sicca.