ANO5 and autosomal recessive limb-girdle muscular dystrophy type 2A: In our cohort of patients, thirty-three are homozygous or compound heterozygous for causative mutations in ANO5. Interestingly only 18/33 are Italian (although they are 90% of the cohort), providing a further evidence of lower frequency of anoctaminopathies in this country [12] where dysferlinopathies and calpainopathies still remain the most common form of LGMD [28].