PVT1 and gastric cancer: To further validate the role of EZH2 in gastric cancer, we detected the EZH2 expression in 30 pairs of gastric cancer tissues and corresponding adjacent tissues by IHC analysis and found that EZH2 was up-regulated in gastric cancer tissues, and the expression of EZH2 was positively correlated with PVT1 expression (Figure 6A).