Moreover, we also compared other biochemical parameters with different ApoE genotypes between hyperuricemia patients and controls and found that both groups of subjects with the ApoE2 allele had a lower uric acid and LDL-C level than those with the ApoE3 allele and ApoE4 allele (p <0.05; Table 4). The gene discussed is APOE; the disease is hyperuricemia.