NUMB and lung adenocarcinoma: Considering that RBM10v1(V354) expression correlated with preferential NUMB exon 11 exclusion and RBM10v1(V354E) expression correlated with preferential NUMB exon 11 inclusion [2] and that expression of the exon 11 retaining NUMB transcript is frequently increased in lung adenocarcinomas [19], one might predict that (a) downregulation of RBM10v1(V354) is one means by which lung cancer cells circumvent proliferation controls, and (b) more RBM10v1(V354del) than RBM10v1(V354) is expressed in lung cancers.