While a qRT-PCR analysis by Tosolini et al. showed that a Th1 cluster and high FOXP3 expression were correlated with improved disease-free survival in colon cancer, corresponding with our results, this group also found a correlation between a high Th1/Th17 gene cluster ratio and improved disease-free survival [32]. Here, FOXP3 is linked to malignant colon neoplasm.