IL17A and neoplasm: While high expression of T cell markers was correlated with improved prognosis, and high expression of angiogenesis marker VEGFA was correlated with poor prognosis, IL17 expressed by Th17 cells could counteract the tumour promoting effects of IL6, even more so combined with a Th2 response characterized by IL5. A proposed model of the factors most relevant for disease outcome is shown in Figure 4.