CASP3 and familial pancreatic carcinoma: Combination treatment with resveratrol and black tea at low dose synergistically inhibits the growth of skin cancer through induction of apoptosis and inhibition of MAPK signaling [10], and the combination of curcumin with garcinol induces apoptosis through increased activity of caspases 3 and 9 in pancreatic cancer cells (BxPC-3 PaCa and PANC-1) [13].