IFNG and Miyoshi myopathy: As it is well known that IL-12 and IL-18 have pronounced synergy in eliciting IFN-γ secretion from NK cells [29], we show that contrary to significantly induced MFI of IFN-γ in the entire population of cells, especially in CD56bright+ subset in HC, in MM patients only the bright subset produces significantly higher level of IFN-γ after combined IL-12 and IL-18 stimulation.