In univariate analysis of the 6-month outcome, predictors of poor functional outcome were lower GCS score on admission (P = 0.004), larger hematoma volume (P = 0.004), intraventricular extension (P = 0.047), midline shift (P = 0.005), and NF-κB activation (P < 0.0001). The gene discussed is NFKB1; the disease is hematoma.