RNAseq and WGS data showed that the three HER2-fusion-positive GC patients were negative for HER3, BRAF, KRAS, PI3KCA, and HER2 mutations, and negative for amplifications of FGFR2 and cMET (data no shown), which are common genetic alterations identified in GC [18]. The gene discussed is FGFR2; the disease is gastric cancer.