CDK6 and melanoma: When we crossed this list with the list of down regulated mRNAs in miR-377-expressing melanoma cells, we found 4 putative transcripts with miR-377-binding sites: E2F3 (a putative target of miR-377 in 6 out of 10 software), MAP3K7 (in 4 out of 10), KRAS (in 5 out of 10) and CDK6 (in 5 out of 10).